Mental Health and Childhood Cancer

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Childhood cancer is increasingly being cured, the 5-year survival rate is now just over 80%. But cure often comes at the price of long-term damage, both physical and mental1.


of families say that their child's mental health has been impacted by their cancer treatment in the short-term2


of families say that their child's mental health has been impacted by their cancer treatment in the long-term2


of families have had breakdowns within the family unit due to the impact of childhood cancer2

Effects on Family Members

Both mothers and siblings experience elevated and prolonged need for mental health-related health care as compared with the general population.


The diagnosis and treatment of childhood cancer is a significant source of stress for the parents. They must shoulder the emotional and financial burdens of caring for a severely ill child. Even with increasing survival rates, cancer treatment requires prolonged, complicated, and intensive treatment protocols that can significantly affect the quality of life for the child as well as the whole family. It has been shown that mothers experienced a 40% increased rate of mental health-related outpatient visits compared with their peers. The prevalence of specific psychiatric conditions tends to differ among parents of children with cancer, ranging from 5% to 65% for anxiety and 7% to 91% for depression. Through significant correlation of mental health outcomes within families suggests that mental health needs in one member may justify the evaluation of the rest of the family.


Siblings need to be considered during the course of treatment of a child with cancer. Siblings often feel as though their needs are less important than those of their sick brother or sister, but they experience the same emotions in reaction to the diagnosis of cancer (shock, helplessness, sadness) plus jealousy because they do not have all of the doctors and staff worrying about their needs. The healthy sibling may feel isolated if parents spend a lot of time in the hospital, or the sibling has to spend time with friends or extended family throughout treatment. Disruptions in the sibling’s normal life and routines can lead to problems in school, behaviour issues, anger, or withdrawal. Hospital programs that include siblings in their programs and those that have specific programs for siblings are increasingly being developed

Do you or your child need help?

If you feel that you or your child needs help, please reach out to your family, a friend, your family doctor, someone you trust, or to some of the resources below. You are not alone.

Some Statistics

  • Almost half of parents (48%) say that their child’s cancer diagnosis has caused them financial stress2.

  • 43% stating that their child’s cancer had led to job loss or the need to significantly reduce hours2.

  • One in five (22%) stated that they felt they had received little or no information about the long-term side effects that their child may suffer2.

Affects on Children Through Different Stages of Development

The way a child is affected by cancer and their psychological response varies with their developmental age at diagnosis. Treatment can interfere with a child’s normal development, activities, and social interactions through repeated school absences, losing contact with friends due to medical isolation from infections, and other disruptions of daily activities4.

Infants and Toddlers

Infants and toddlers mostly respond to how safe and comfortable they feel. Allowing the child the ability to maintain a secure attachment to their primary caregiver while in the hospital going through treatment is a priority; hence, caregiver “rooming in” has been a vast improvement in hospital care allowing them to continue to develop as normally as possible4.

Preschool Age

Preschool children may believe that their cancer is a punishment for being bad and that the treatments and procedures are additional punishments. Family is still the core social interaction for children this age, so prolonged separations from family members can cause anxiety and be very difficult for the patient and the treatment team4.

School Age

School age children can understand simple explanations of their cancer and learn the names of their medications and procedures. At this age, rules become very important, so having a diagnosis of cancer is disruptive and frustrating. Many children question why and can become confused or distressed because there are no identifiable causes of most childhood cancers. Missing school and disrupted friendships are common and upsetting since school and friends play such an important role in social development in this age group4.


The developmental issues facing teens include finding their identity, establishing independence, and seeking intimacy with peers which can be extremely difficult while having to endure cancer treatment. Another important concern for teens is physical attractiveness; losing hair, losing/gaining weight, and having scars can negatively impact a teenager’s self-esteem. They may be reluctant to have friends visit or may isolate themselves at a time when friends and peer groups are extremely important for social development4.

Emotional and mental health issues are the most common long-term side effect for childhood cancer patients (34%), including anxiety, post-traumatic stress disorder, and depression2.


Support for children with cancer and their families has grown and has been more fully integrated into pediatric care over the past several decades. Increasing acceptance of the importance of addressing mental health has led to oncologists referring patients to pediatric mental health specialists.

There is a risk of mental health disorders in cancer patients, exposed by anxieties of diagnosis, therapy, and disruption of activities of daily living. The side effects of cancer treatment itself (chemotherapy, surgery, radiation) can lead to difficulties in cognition, poor coping skills, and disordered behaviour. These stressors and difficulties do not end with the completion of treatment but follow children through growing up, going to school, and surviving longer.


  1. Mertens, A. C., & Marchak, J. G. (2015). Mental health status of adolescent cancer survivors. Clinical Oncology in Adolescents and Young Adults, 87-95. doi:10.2147/coaya.s49174

  2. Cancer treatment: Mental health: Children with Cancer UK. (2020, December 06). Retrieved from

  3. Van Warmerdam, J., Sutradhar, R., Kurdyak, P., Lau, C., Pole, J., Nathan, P., & Gupta, S. (2019). Long-Term Mental Health Outcomes in Mothers and Siblings of Children With Cancer: A Population-Based, Matched Cohort Study. Journal of Clinical Oncology, 38(1). doi:10.1200/JCO.19.01382

  4. Nicole Mavrides & Maryland Pao (2014) Updates in paediatric psycho-oncology, International Review of Psychiatry, 26:1, 63-73, DOI: 10.3109/09540261.2013.870537